1zj7

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Image:1zj7.png

Template:STRUCTURE 1zj7

Crystal structure of a complex of mutant HIV-1 protease (A71V, V82T, I84V) with a hydroxyethylamine peptidomimetic inhibitor BOC-PHE-PSI[S-CH(OH)CH2NH]-PHE-GLU-PHE-NH2

Template:ABSTRACT PUBMED 16970402

About this Structure

1ZJ7 is a 2 chains structure of sequences from Human immunodeficiency virus. Full crystallographic information is available from OCA.

Reference

  • Skalova T, Dohnalek J, Duskova J, Petrokova H, Hradilek M, Soucek M, Konvalinka J, Hasek J. HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site. J Med Chem. 2006 Sep 21;49(19):5777-84. PMID:16970402 doi:10.1021/jm0605583

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