User:User:Marcia Ivonne Peña Paz

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BMAL_1

Brain and muscle Arnt like 1. Also known as MOP3

It is part of the transcriptional/translational feed back loop of the circadian timing system.

It forms an heterodimer with CLOCK or NPAS2 and both translocate into the nucleus. The heterodimer binds to E-box promoter elements of target genes, . It modulates the expression of the genes Cry 1/2, Per 1/2/3, Dbp, Rorα, Pparα, Namt, Ccg, MyoD, CKIε.

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Marcia Ivonne Peña Paz

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