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Carnitine acetyltransferase

The carnitine acetyltransferases (also known as CATs) belong to the family of enzymes known as the carnitine acyltransferases, which also includes carnitine octanoyltransferases (CrOTs) and carnitine palmityltransferase (CPTs). The three known classes of carnitine acyltransferases differ in their acyl group specificity. Carnitine acetyltransferase has a substrate preference for short chain acyl-CoAs whereas carnitine palmityltransferases and carnitine palmityltransferases show preference for long chain acyl-CoAs.They are found in the mitochondrial matrix. Carnitine acetyltransferases are localized in both the outer membrane and the inner membrane.

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