3tam

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Image:3tam.png

Template:STRUCTURE 3tam

Crystal structure of HIV-1 reverse transcriptase (K103N mutant) in complex with inhibitor M06

Template:ABSTRACT PUBMED 21985673

About this Structure

3tam is a 2 chain structure with sequence from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.

Reference

  • Gomez R, Jolly S, Williams TM, Vacca JP, Torrent M, McGaughey G, Lai MT, Felock PJ, Munshi V, Distefano D, Flynn JA, Miller MD, Yan Y, Reid JC, Sanchez R, Liang Y, Paton B, Wan BL, Anthony NJ. Design and Synthesis of conformationally Constrained Inhibitors of Non-Nucleoside Reverse Transcriptase. J Med Chem. 2011 Oct 10. PMID:21985673 doi:10.1021/jm2010173

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OCA

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