3t19

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Image:3t19.png

Template:STRUCTURE 3t19

Crystal structure of HIV-1 reverse transcriptase (wild type) in complex with inhibitor M05

Template:ABSTRACT PUBMED 21985673

About this Structure

3t19 is a 2 chain structure with sequence from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.

Reference

  • Gomez R, Jolly S, Williams TM, Vacca JP, Torrent M, McGaughey G, Lai MT, Felock PJ, Munshi V, Distefano D, Flynn JA, Miller MD, Yan Y, Reid JC, Sanchez R, Liang Y, Paton B, Wan BL, Anthony NJ. Design and Synthesis of conformationally Constrained Inhibitors of Non-Nucleoside Reverse Transcriptase. J Med Chem. 2011 Oct 10. PMID:21985673 doi:10.1021/jm2010173

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OCA

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