3u6j

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Template:STRUCTURE 3u6j

Crystal structure of the VEGFR2 kinase domain in complex with a pyrazolone inhibitor

About this Structure

3u6j is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Liu L, Norman MH, Lee M, Xi N, Siegmund A, Boezio AA, Booker S, Choquette D, D'Angelo ND, Germain J, Yang K, Yang Y, Zhang Y, Bellon SF, Whittington DA, Harmange JC, Dominguez C, Kim TS, Dussault I. Structure-Based Design of Novel Class II c-Met Inhibitors: 2. SAR and Kinase Selectivity Profiles of the Pyrazolone Series. J Med Chem. 2012 Feb 24. PMID:22320327 doi:http://dx.doi.org/10.1021/jm201331s

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