3g8o

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Template:STRUCTURE 3g8o

Progesterone Receptor with bound Pyrrolidine 22

Template:ABSTRACT PUBMED 19595590

About this Structure

3G8O is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Thompson SK, Washburn DG, Frazee JS, Madauss KP, Hoang TH, Lapinski L, Grygielko ET, Glace LE, Trizna W, Williams SP, Duraiswami C, Bray JD, Laping NJ. Rational design of orally-active, pyrrolidine-based progesterone receptor partial agonists. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4777-80. Epub 2009 Jun 17. PMID:19595590 doi:10.1016/j.bmcl.2009.06.055

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