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P53 protein

Introduction

	Cancer is one of the most popular diseases occurring today. Research has been done on this issue for an extended amount of years to figure out how this devastating case works and what factors are contributing to this devastating illness. Throughout time there have been some successful answers while some things still remain in question during this existent investigation. One of the most interesting roles in the fight with cancer happens to be a protein quite phenomenal to cell life. This protein is none other than the unique p53 protein. P53 protein is an extremely important system in cell cycle control and the area of cancer. This protein was researched by Bert Vogelstein, David Lane, and Arnold Levine. The p53 protein is also called the guardian of the genome because of the role it has in checkpoint pathways of the cell cycle. This protein is located on chromosome 17 on the short arm which is where the open reading frames occur for proteins. The p53 protein was discovered through co-purification with a large T antigen in SV40 virus transformed cells.