Sandbox Reserved 483

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Revision as of 21:28, 1 May 2012 by Roberto Quinones (Talk | contribs)
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This Sandbox is Reserved from 13/03/2012, through 01/06/2012 for use in the course "Proteins and Molecular Mechanisms" taught by Robert B. Rose at the North Carolina State University, Raleigh, NC USA. This reservation includes Sandbox Reserved 451 through Sandbox Reserved 500.
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Thrombin (Factor IIa)

Introduction


Thrombin (Factor IIa)

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Thrombin is a Trypsin like Serine protease (1). It uses the serine amino acid to specifically cleave fibrinogen into fibrin (3).This forms a blood clot which stops blood from leaking out of the blood circulatory system in case of a rupture. It also catalyzes the activation of factor XIII which stabilizes the fibrin network (3).

Structure


Mechanism of action


Image:Thrombincascade.jpg

Applications


References


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