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4ago

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Image:4ago.jpg

Template:STRUCTURE 4ago

Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5174

Template:ABSTRACT PUBMED 17015838

About this Structure

4ago is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838

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OCA

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