3vp1

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Template:STRUCTURE 3vp1

Crystal structure of human glutaminase in complex with L-glutamate and BPTES

Template:ABSTRACT PUBMED 22538822

About this Structure

3vp1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Thangavelu K, Pan CQ, Karlberg T, Balaji G, Uttamchandani M, Suresh V, Schuler H, Low BC, Sivaraman J. Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7705-10. Epub 2012 Apr 26. PMID:22538822 doi:10.1073/pnas.1116573109

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