2v5w
From Proteopedia
Contents |
Crystal structure of HDAC8-substrate complex
Template:ABSTRACT PUBMED 17721440
About this Structure
2v5w is a 5 chain structure of Histone deacetylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Vannini A, Volpari C, Gallinari P, Jones P, Mattu M, Carfi A, De Francesco R, Steinkuhler C, Di Marco S. Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8-substrate complex. EMBO Rep. 2007 Sep;8(9):879-84. Epub 2007 Aug 10. PMID:17721440
- Dowling DP, Gantt SL, Gattis SG, Fierke CA, Christianson DW. Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry. 2008 Dec 23;47(51):13554-63. PMID:19053282 doi:10.1021/bi801610c
Categories: Homo sapiens | Carfi, A. | Defrancesco, R. | Gallinari, P. | Jones, P. | Marco, S Di. | Mattu, M. | Steinkuhler, C. | Vannini, A. | Volpari, C. | Chromatin | Chromatin regulator | Deacetylation | Hdac | Hdac8 | Histone deacetylase | Hydrolase | Hydrolase-hydrolase substrate complex | Nuclear protein | Nucleus | P53 | Peptidic substrate | Repressor | Transcription | Transcription regulation
