2oh4

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Template:STRUCTURE 2oh4

Crystal structure of Vegfr2 with a benzimidazole-urea inhibitor

Template:ABSTRACT PUBMED 17676829

About this Structure

2OH4 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hasegawa M, Nishigaki N, Washio Y, Kano K, Harris PA, Sato H, Mori I, West RI, Shibahara M, Toyoda H, Wang L, Nolte RT, Veal JM, Cheung M. Discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors. J Med Chem. 2007 Sep 6;50(18):4453-70. Epub 2007 Aug 4. PMID:17676829 doi:10.1021/jm0611051

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