1ef3

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Image:1ef3.png

Template:STRUCTURE 1ef3

FIDARESTAT BOUND TO HUMAN ALDOSE REDUCTASE

Template:ABSTRACT PUBMED 10882376

About this Structure

1EF3 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Oka M, Matsumoto Y, Sugiyama S, Tsuruta N, Matsushima M. A potent aldose reductase inhibitor, (2S,4S)-6-fluoro-2', 5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide (Fidarestat): its absolute configuration and interactions with the aldose reductase by X-ray crystallography. J Med Chem. 2000 Jun 15;43(12):2479-83. PMID:10882376

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