2p83

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Image:2p83.png

Template:STRUCTURE 2p83

Potent and selective isophthalamide S2 hydroxyethylamine inhibitor of BACE1

Template:ABSTRACT PUBMED 17434734

About this Structure

2P83 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kortum SW, Benson TE, Bienkowski MJ, Emmons TL, Prince DB, Paddock DJ, Tomasselli AG, Moon JB, LaBorde A, TenBrink RE. Potent and selective isophthalamide S2 hydroxyethylamine inhibitors of BACE1. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3378-83. Epub 2007 Apr 3. PMID:17434734 doi:10.1016/j.bmcl.2007.03.096

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