3k5g

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Image:3k5g.jpg

Template:STRUCTURE 3k5g

Human bace-1 complex with bjc060

Template:ABSTRACT PUBMED 20172717

About this Structure

3K5G is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hanessian S, Shao Z, Betschart C, Rondeau JM, Neumann U, Tintelnot-Blomley M. Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1924-7. Epub 2010 Feb 2. PMID:20172717 doi:10.1016/j.bmcl.2010.01.139

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