2azr

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Image:2azr.png

Template:STRUCTURE 2azr

Crystal structure of PTP1B with Bicyclic Thiophene inhibitor

Template:ABSTRACT PUBMED 16303309

About this Structure

2AZR is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Moretto AF, Kirincich SJ, Xu WX, Smith MJ, Wan ZK, Wilson DP, Follows BC, Binnun E, Joseph-McCarthy D, Foreman K, Erbe DV, Zhang YL, Tam SK, Tam SY, Lee J. Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors. Bioorg Med Chem. 2006 Apr 1;14(7):2162-77. Epub 2005 Nov 21. PMID:16303309 doi:10.1016/j.bmc.2005.11.005

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