2dtg

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Image:2dtg.png

Template:STRUCTURE 2dtg

Insulin receptor (IR) ectodomain in complex with fab's

Template:ABSTRACT PUBMED 16957736

About this Structure

2DTG is a 5 chains structure of sequences from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

Reference

  • McKern NM, Lawrence MC, Streltsov VA, Lou MZ, Adams TE, Lovrecz GO, Elleman TC, Richards KM, Bentley JD, Pilling PA, Hoyne PA, Cartledge KA, Pham TM, Lewis JL, Sankovich SE, Stoichevska V, Da Silva E, Robinson CP, Frenkel MJ, Sparrow LG, Fernley RT, Epa VC, Ward CW. Structure of the insulin receptor ectodomain reveals a folded-over conformation. Nature. 2006 Sep 14;443(7108):218-21. Epub 2006 Sep 6. PMID:16957736 doi:10.1038/nature05106

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