1ym2

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Image:1ym2.png

Template:STRUCTURE 1ym2

Crystal structure of human beta secretase complexed with NVP-AUR200

Template:ABSTRACT PUBMED 16078837

About this Structure

1YM2 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hanessian S, Yun H, Hou Y, Yang G, Bayrakdarian M, Therrien E, Moitessier N, Roggo S, Veenstra S, Tintelnot-Blomley M, Rondeau JM, Ostermeier C, Strauss A, Ramage P, Paganetti P, Neumann U, Betschart C. Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics. J Med Chem. 2005 Aug 11;48(16):5175-90. PMID:16078837 doi:10.1021/jm050142+

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