1vyq

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Image:1vyq.png

Template:STRUCTURE 1vyq

Contents

NOVEL INHIBITORS OF PLASMODIUM FALCIPARUM DUTPASE PROVIDE A PLATFORM FOR ANTI-MALARIAL DRUG DESIGN

Template:ABSTRACT PUBMED 15698576

About this Structure

1vyq is a 3 chain structure of Deoxyuridine 5'-triphosphate nucleotidohydrolase with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

See Also

Reference

  • Whittingham JL, Leal I, Nguyen C, Kasinathan G, Bell E, Jones AF, Berry C, Benito A, Turkenburg JP, Dodson EJ, Ruiz Perez LM, Wilkinson AJ, Johansson NG, Brun R, Gilbert IH, Gonzalez Pacanowska D, Wilson KS. dUTPase as a platform for antimalarial drug design: structural basis for the selectivity of a class of nucleoside inhibitors. Structure. 2005 Feb;13(2):329-38. PMID:15698576 doi:10.1016/j.str.2004.11.015

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