1qxz

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Image:1qxz.png

Template:STRUCTURE 1qxz

Crystal structure of S. aureus methionine aminopeptidase in complex with a ketoheterocycle inhibitor 119

Template:ABSTRACT PUBMED 14998322

About this Structure

1QXZ is a 1 chain structure of sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Douangamath A, Dale GE, D'Arcy A, Almstetter M, Eckl R, Frutos-Hoener A, Henkel B, Illgen K, Nerdinger S, Schulz H, Mac Sweeney A, Thormann M, Treml A, Pierau S, Wadman S, Oefner C. Crystal structures of Staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate. J Med Chem. 2004 Mar 11;47(6):1325-8. PMID:14998322 doi:http://dx.doi.org/10.1021/jm034188j

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