2eb2
From Proteopedia
Contents |
Crystal structure of mutated EGFR kinase domain (G719S)
Template:ABSTRACT PUBMED 22349823
About this Structure
2eb2 is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yoshikawa S, Kukimoto-Niino M, Parker L, Handa N, Terada T, Fujimoto T, Terazawa Y, Wakiyama M, Sato M, Sano S, Kobayashi T, Tanaka T, Chen L, Liu ZJ, Wang BC, Shirouzu M, Kawa S, Semba K, Yamamoto T, Yokoyama S. Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor. Oncogene. 2012 Feb 20. doi: 10.1038/onc.2012.21. PMID:22349823 doi:10.1038/onc.2012.21
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Chen, L. | Kukimoto-Niino, M. | Liu, Z J. | RSGI, RIKEN Structural Genomics/Proteomics Initiative. | Senba, K. | Shirouzu, M. | Wang, B C. | Yamamoto, T. | Yokoyama, S. | Yoshikawa, S. | Atp-binding | Cell cycle | Disease mutation | Ec 2 7.10 1 | Kinase | National project on protein structural and functional analyse | Nppsfa | Phosphorylation | Receptor | Riken structural genomics/proteomics initiative | Rsgi | Structural genomic | Transferase | Transmembrane | Tyrosine-protein kinase
