3hky

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Image:3hky.jpg

Template:STRUCTURE 3hky

HCV NS5B polymerase genotype 1b in complex with 1,5 benzodiazepine 6

Template:ABSTRACT PUBMED 20071590

About this Structure

3HKY is a 2 chains structure with sequences from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.

Reference

  • Nyanguile O, Devogelaere B, Vijgen L, Van den Broeck W, Pauwels F, Cummings MD, De Bondt HL, Vos AM, Berke JM, Lenz O, Vandercruyssen G, Vermeiren K, Mostmans W, Dehertogh P, Delouvroy F, Vendeville S, VanDyck K, Dockx K, Cleiren E, Raboisson P, Simmen KA, Fanning GC. 1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus. J Virol. 2010 Mar;84(6):2923-34. Epub 2010 Jan 13. PMID:20071590 doi:10.1128/JVI.01980-09

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