3dm6

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Image:3dm6.jpg

Template:STRUCTURE 3dm6

Beta-secretase 1 complexed with statine-based inhibitor

Template:ABSTRACT PUBMED 18842420

About this Structure

3DM6 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues., Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B, Bioorg Med Chem. 2008 Nov 1;16(21):9471-86. Epub 2008 Sep 19. PMID:18842420

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