3q2h

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Template:STRUCTURE 3q2h

Adamts1 in complex with N-hydroxyformamide inhibitors of ADAM-TS4

Template:ABSTRACT PUBMED 21300546

About this Structure

3q2h is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • De Savi C, Pape A, Cumming JG, Ting A, Smith PD, Burrows JN, Mills M, Davies C, Lamont S, Milne D, Cook C, Moore P, Sawyer Y, Gerhardt S. The design and synthesis of novel N-hydroxyformamide inhibitors of ADAM-TS4 for the treatment of osteoarthritis. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1376-81. Epub 2011 Jan 18. PMID:21300546 doi:10.1016/j.bmcl.2011.01.036

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