1bl0

From Proteopedia

Revision as of 09:36, 20 November 2007 by OCA (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
Image:1bl0.gif

1bl0, resolution 2.300Å

Drag the structure with the mouse to rotate

MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN (MARA)/DNA COMPLEX

Overview

A crystal structure for a member of the AraC prokaryotic transcriptional, activator family, MarA, in complex with its cognate DNA-binding site is, described. MarA consists of two similar subdomains, each containing a, helix-turn-helix DNA-binding motif. The two recognition helices of the, motifs are inserted into adjacent major groove segments on the same face, of the DNA but are separated by only 27 A thereby bending the DNA by, approximately 35 degrees. Extensive interactions between the recognition, helices and the DNA major groove provide the sequence specificity.

About this Structure

1BL0 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator., Rhee S, Martin RG, Rosner JL, Davies DR, Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10413-8. PMID:9724717

Page seeded by OCA on Tue Nov 20 11:44:06 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1bl0"
Personal tools