3ocg

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Template:STRUCTURE 3ocg

Contents 1 P38 Alpha kinase complexed with a 5-amino-pyrazole based inhibitor 2 About this Structure 3 See Also 4 Reference

P38 Alpha kinase complexed with a 5-amino-pyrazole based inhibitor

Template:ABSTRACT PUBMED 21035336

About this Structure

3ocg is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Mitogen-activated protein kinase

Reference

• Das J, Moquin RV, Dyckman AJ, Li T, Pitt S, Zhang R, Shen DR, McIntyre KW, Gillooly K, Doweyko AM, Newitt JA, Sack JS, Zhang H, Kiefer SE, Kish K, McKinnon M, Barrish JC, Dodd JH, Schieven GL, Leftheris K. 5-Amino-pyrazoles as potent and selective p38alpha inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6886-9. Epub 2010 Oct 13. PMID:21035336 doi:10.1016/j.bmcl.2010.10.034