1ni1

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Image:1ni1.png

Template:STRUCTURE 1ni1

Imidazole and cyanophenyl farnesyl transferase inhibitors

Template:ABSTRACT PUBMED 12699757

About this Structure

1NI1 is a 2 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Tong Y, Lin NH, Wang L, Hasvold L, Wang W, Leonard N, Li T, Li Q, Cohen J, Gu WZ, Zhang H, Stoll V, Bauch J, Marsh K, Rosenberg SH, Sham HL. Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability. Bioorg Med Chem Lett. 2003 May 5;13(9):1571-4. PMID:12699757

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