1xbo

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Image:1xbo.png

Template:STRUCTURE 1xbo

PTP1B complexed with Isoxazole Carboxylic Acid

Template:ABSTRACT PUBMED 15482920

About this Structure

1XBO is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhao H, Liu G, Xin Z, Serby MD, Pei Z, Szczepankiewicz BG, Hajduk PJ, Abad-Zapatero C, Hutchins CW, Lubben TH, Ballaron SJ, Haasch DL, Kaszubska W, Rondinone CM, Trevillyan JM, Jirousek MR. Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5543-6. PMID:15482920 doi:10.1016/j.bmcl.2004.08.063

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