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3nlt

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Revision as of 06:23, 19 January 2011 by OCA (Talk | contribs)
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Image:3nlt.jpg

Template:STRUCTURE 3nlt

Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'S,4'S)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}- N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride

Template:ABSTRACT PUBMED 20843082

About this Structure

3nlt is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Xue F, Li H, Delker SL, Fang J, Martasek P, Roman LJ, Poulos TL, Silverman RB. Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase. J Am Chem Soc. 2010 Oct 13;132(40):14229-38. PMID:20843082 doi:10.1021/ja106175q

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OCA

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