3gen
From Proteopedia
The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound
Template:ABSTRACT PUBMED 20052711
About this Structure
3GEN is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Marcotte DJ, Liu YT, Arduini RM, Hession CA, Miatkowski K, Wildes CP, Cullen PF, Hong V, Hopkins BT, Mertsching E, Jenkins TJ, Romanowski MJ, Baker DP, Silvian LF. Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for tec family kinases. Protein Sci. 2010 Jan 5. PMID:20052711 doi:10.1002/pro.321
Page seeded by OCA on Wed Mar 10 15:13:53 2010
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Arduini, R M. | Baker, D P. | Cullen, P F. | Hession, C A. | Hopkins, B. | Jenkins, T J. | Liu, Y T. | Marcotte, D J. | Mertsching, E. | Miatkowski, K. | Romanowski, M J. | Silvian, L F. | Wildes, C P. | Acetylation | Atp-binding | Bruton's tyrosine kinase | Complex | Cytoplasm | Disease mutation | Kinase | Membrane | Metal-binding | Nucleotide-binding | Nucleus | Phosphoprotein | Polymorphism | Sh2 domain | Sh3 domain | Tec-family | Transferase | Tyrosine-protein kinase | Zinc | Zinc-finger
