1tco

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Image:1tco.png

Template:STRUCTURE 1tco

TERNARY COMPLEX OF A CALCINEURIN A FRAGMENT, CALCINEURIN B, FKBP12 AND THE IMMUNOSUPPRESSANT DRUG FK506 (TACROLIMUS)

Template:ABSTRACT PUBMED 7543369

About this Structure

1TCO is a 3 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Griffith JP, Kim JL, Kim EE, Sintchak MD, Thomson JA, Fitzgibbon MJ, Fleming MA, Caron PR, Hsiao K, Navia MA. X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex. Cell. 1995 Aug 11;82(3):507-22. PMID:7543369

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