3ixj

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Image:3ixj.jpg

Template:STRUCTURE 3ixj

Crystal structure of beta-secretase 1 in complex with selective beta-secretase 1 inhibitor

Template:ABSTRACT PUBMED 20128595

About this Structure

3IXJ is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bjorklund C, Oscarson S, Benkestock K, Borkakoti N, Jansson K, Lindberg J, Vrang L, Hallberg A, Rosenquist A, Samuelsson B. Design and synthesis of potent and selective BACE-1 inhibitors. J Med Chem. 2010 Feb 25;53(4):1458-64. PMID:20128595 doi:10.1021/jm901168f

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