3gzq

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Image:3gzq.png

Template:STRUCTURE 3gzq

Contents

HUMAN SOD1 A4V Metal-free Variant

Template:ABSTRACT PUBMED 19800308

Disease

Known disease associated with this structure: Amyotrophic lateral sclerosis, due to SOD1 deficiency OMIM:[147450]

About this Structure

3GZQ is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Galaleldeen A, Strange RW, Whitson LJ, Antonyuk SV, Narayana N, Taylor AB, Schuermann JP, Holloway SP, Hasnain SS, Hart PJ. Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A. Arch Biochem Biophys. 2009 Dec;492(1-2):40-7. Epub 2009 Oct 1. PMID:19800308 doi:10.1016/j.abb.2009.09.020

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