2c8y

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Image:2c8y.png

Template:STRUCTURE 2c8y

THROMBIN INHIBITORS

Template:ABSTRACT PUBMED 16480269

About this Structure

2C8Y is a 3 chains structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Howard N, Abell C, Blakemore W, Chessari G, Congreve M, Howard S, Jhoti H, Murray CW, Seavers LC, van Montfort RL. Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors. J Med Chem. 2006 Feb 23;49(4):1346-55. PMID:16480269 doi:10.1021/jm050850v

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