2uxz

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Image:2uxz.png

Template:STRUCTURE 2uxz

TWO-CARBON-ELONGATED HIV-1 PROTEASE INHIBITORS WITH A TERTIARY-ALCOHOL-CONTAINING TRANSITION-STATE MIMIC

Template:ABSTRACT PUBMED 18215014

About this Structure

2UXZ is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Wu X, Ohrngren P, Ekegren JK, Unge J, Unge T, Wallberg H, Samuelsson B, Hallberg A, Larhed M. Two-carbon-elongated HIV-1 protease inhibitors with a tertiary-alcohol-containing transition-state mimic. J Med Chem. 2008 Feb 28;51(4):1053-7. Epub 2008 Jan 24. PMID:18215014 doi:10.1021/jm070680h

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