3fv8

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Image:3fv8.png

Template:STRUCTURE 3fv8

JNK3 bound to piperazine amide inhibitor, SR2774.

Template:ABSTRACT PUBMED 19433357

About this Structure

3FV8 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Shin Y, Chen W, Habel J, Duckett D, Ling YY, Koenig M, He Y, Vojkovsky T, LoGrasso P, Kamenecka TM. Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3344-7. Epub 2009 Mar 26. PMID:19433357 doi:10.1016/j.bmcl.2009.03.086

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