1cdm

From Proteopedia

Revision as of 10:15, 20 November 2007 by OCA (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
Image:1cdm.gif

1cdm, resolution 2.0Å

Drag the structure with the mouse to rotate

MODULATION OF CALMODULIN PLASTICITY IN MOLECULAR RECOGNITION ON THE BASIS OF X-RAY STRUCTURES

Overview

Calmodulin is the primary calcium-dependent signal transducer and, regulator of a wide variety of essential cellular functions. The structure, of calcium-calmodulin bound to the peptide corresponding to the, calmodulin-binding domain of brain calmodulin-dependent protein kinase II, alpha was determined to 2 angstrom resolution. A comparison to two other, calcium-calmodulin structures reveals how the central helix unwinds in, order to position the two domains optimally in the recognition of, different target enzymes and clarifies the role of calcium in maintaining, recognition-competent domain structures.

About this Structure

1CDM is a Protein complex structure of sequences from Bos taurus with CA as ligand. Full crystallographic information is available from OCA.

Reference

Modulation of calmodulin plasticity in molecular recognition on the basis of x-ray structures., Meador WE, Means AR, Quiocho FA, Science. 1993 Dec 10;262(5140):1718-21. PMID:8259515

Page seeded by OCA on Tue Nov 20 12:22:11 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1cdm"
Personal tools