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2f47

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Revision as of 22:05, 14 March 2011 by OCA (Talk | contribs)
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Image:2f47.png

Template:STRUCTURE 2f47

Xray crystal structure of T4 lysozyme mutant L20/R63A liganded to methylguanidinium

Template:ABSTRACT PUBMED 16600969

About this Structure

2f47 is a 1 chain structure with sequence from Enterobacteria phage t4. Full crystallographic information is available from OCA.

Reference

  • Yousef MS, Bischoff N, Dyer CM, Baase WA, Matthews BW. Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme. Protein Sci. 2006 Apr;15(4):853-61. PMID:16600969 doi:15/4/853
  • Yousef MS, Baase WA, Matthews BW. Use of sequence duplication to engineer a ligand-triggered, long-distance molecular switch in T4 lysozyme. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11583-6. Epub 2004 Jul 30. PMID:15286283 doi:10.1073/pnas.0404482101
  • Sagermann M, Baase WA, Matthews BW. Structural characterization of an engineered tandem repeat contrasts the importance of context and sequence in protein folding. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6078-83. PMID:10339544
  • Sagermann M, Gay L, Matthews BW. Long-distance conformational changes in a protein engineered by modulated sequence duplication. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9191-5. Epub 2003 Jul 17. PMID:12869697 doi:10.1073/pnas.1633549100

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