3jzr

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Image:3jzr.png

Template:STRUCTURE 3jzr

Human MDM2 liganded with a 12mer peptide inhibitor (pDI6W)

Template:ABSTRACT PUBMED 19910468

About this Structure

3JZR is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Phan J, Li Z, Kasprzak A, Li B, Sebti S, Guida W, Schonbrunn E, Chen J. Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX. J Biol Chem. 2010 Jan 15;285(3):2174-83. Epub 2009 Nov 12. PMID:19910468 doi:10.1074/jbc.M109.073056

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