1izi
From Proteopedia
Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants
Template:ABSTRACT PUBMED 12460574
About this Structure
1IZI is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Weber J, Mesters JR, Lepsik M, Prejdova J, Svec M, Sponarova J, Mlcochova P, Skalicka K, Strisovsky K, Uhlikova T, Soucek M, Machala L, Stankova M, Vondrasek J, Klimkait T, Kraeusslich HG, Hilgenfeld R, Konvalinka J. Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains. J Mol Biol. 2002 Dec 6;324(4):739-54. PMID:12460574
Page seeded by OCA on Mon Feb 16 23:44:33 2009
Categories: HIV-1 retropepsin | Human immunodeficiency virus 1 | Hilgenfeld, R. | Klimkait, T. | Konvalinka, J. | Kraeusslich, H G. | Lepsik, M. | Machala, L. | Mesters, J R. | Mlcochova, P. | Prejdova, J. | Skalicka, K. | Soucek, M. | Sponarova, J. | Stankova, M. | Strisovsky, K. | Svec, M. | Uhlikova, T. | Vondrasek, J. | Weber, J. | Hiv-1 proteinase | Potent inhibitor | Subsite binding | Triple mutant
