3qaq

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Template:STRUCTURE 3qaq

Crystal structure of PI3K-gamma in complex with triazine-benzimidazole 1

Template:ABSTRACT PUBMED 21376583

About this Structure

3qaq is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Peterson EA, Andrews PS, Be X, Boezio AA, Bush TL, Cheng AC, Coats JR, Colletti AE, Copeland KW, Dupont M, Graceffa R, Grubinska B, Harmange JC, Kim JL, Mullady EL, Olivieri P, Schenkel LB, Stanton MK, Teffera Y, Whittington DA, Cai T, La DS. Discovery of triazine-benzimidazoles as selective inhibitors of mTOR. Bioorg Med Chem Lett. 2011 Apr 1;21(7):2064-70. Epub 2011 Feb 12. PMID:21376583 doi:10.1016/j.bmcl.2011.02.007

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