3lxe

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Image:3lxe.jpg

Template:STRUCTURE 3lxe

Human Carbonic Anhydrase I in complex with topiramate

Template:ABSTRACT PUBMED 20505865

About this Structure

3LXE is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Alterio V, Monti SM, Truppo E, Pedone C, Supuran CT, De Simone G. The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex. Org Biomol Chem. 2010 Aug 7;8(15):3528-33. Epub 2010 May 27. PMID:20505865 doi:10.1039/b926832d

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