1o4l

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Image:1o4l.png

Template:STRUCTURE 1o4l

Contents

CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH FRAGMENT2.

Template:ABSTRACT PUBMED 14613321

Disease

Known disease associated with this structure: Colon cancer, advanced OMIM:[190090]

About this Structure

1O4L is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E. Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:14613321 doi:http://dx.doi.org/10.1021/jm020970s

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