This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1csn
From Proteopedia
|
BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP
Overview
The structure of a truncated variant of casein kinase-1 from, Schizosaccharomyces pombe, has been determined in complex with MgATP at, 2.0 A resolution. The model resembles the 'closed', ATP-bound, conformations of the cyclin-dependent kinase 2 and the cAMP-dependent, protein kinase, with clear differences in the structure of surface loops, that impart unique features to casein kinase-1. The structure is of, unphosphorylated, active conformation of casein kinase-1 and the, peptide-binding site is fully accessible to substrate.
About this Structure
1CSN is a Single protein structure of sequence from Schizosaccharomyces pombe with MG, SO4 and ATP as ligands. Full crystallographic information is available from OCA.
Reference
Crystal structure of casein kinase-1, a phosphate-directed protein kinase., Xu RM, Carmel G, Sweet RM, Kuret J, Cheng X, EMBO J. 1995 Mar 1;14(5):1015-23. PMID:7889932
Page seeded by OCA on Tue Nov 20 12:43:38 2007
Categories: Schizosaccharomyces pombe | Single protein | Cheng, X. | Xu, R.M. | ATP | MG | SO4 | Phosphotransferase
