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2v00
From Proteopedia
X-RAY CRYSTAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH COMPOUND 1
Template:ABSTRACT PUBMED 17985861
About this Structure
2V00 is a 1 chain structure of sequence from Cryphonectria parasitica. Full crystallographic information is available from OCA.
Reference
- Geschwindner S, Olsson LL, Albert JS, Deinum J, Edwards PD, de Beer T, Folmer RH. Discovery of a novel warhead against beta-secretase through fragment-based lead generation. J Med Chem. 2007 Nov 29;50(24):5903-11. Epub 2007 Nov 7. PMID:17985861 doi:10.1021/jm070825k
Page seeded by OCA on Tue Feb 17 01:21:00 2009
Categories: Cryphonectria parasitica | Endothiapepsin | Albert, J S. | Beer, T De. | Deinum, J. | Edwards, P D. | Folmer, R H.A. | Geschwindner, S. | Olsson, L L. | Alzheimer's disease | Aspartyl protease | B- secretase | Bace | Fragment hit | Fragment-based lead generation | Hydrolase | Isocytosine | Protease | Surrogate protein | Zymogen
