1xgi

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Template:STRUCTURE 1xgi

AmpC beta-lactamase in complex with 3-(3-nitro-phenylsulfamoyl)-thiophene-2-carboxylic acid

Template:ABSTRACT PUBMED 15796528

About this Structure

1XGI is a 2 chains structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Tondi D, Morandi F, Bonnet R, Costi MP, Shoichet BK. Structure-based optimization of a non-beta-lactam lead results in inhibitors that do not up-regulate beta-lactamase expression in cell culture. J Am Chem Soc. 2005 Apr 6;127(13):4632-9. PMID:15796528 doi:10.1021/ja042984o

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