3ara

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Template:STRUCTURE 3ara

Contents 1 Discovery of Novel Uracil Derivatives as Potent Human dUTPase Inhibitors 2 About this Structure 3 See Also 4 Reference

Discovery of Novel Uracil Derivatives as Potent Human dUTPase Inhibitors

Template:ABSTRACT PUBMED 22404301

About this Structure

3ara is a 3 chain structure of Deoxyuridine 5'-triphosphate nucleotidohydrolase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Deoxyuridine 5'-triphosphate nucleotidohydrolase

Reference

• Miyakoshi H, Miyahara S, Yokogawa T, Chong KT, Taguchi J, Endoh K, Yano W, Wakasa T, Ueno H, Takao Y, Nomura M, Shuto S, Nagasawa H, Fukuoka M. Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors. J Med Chem. 2012 Apr 12;55(7):2960-9. Epub 2012 Mar 26. PMID:22404301 doi:10.1021/jm201627n