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1ia3

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Revision as of 00:42, 17 February 2009 by OCA (Talk | contribs)
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Image:1ia3.png

Template:STRUCTURE 1ia3

Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) is displaced by 5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW995)

Template:ABSTRACT PUBMED 11520201

About this Structure

1IA3 is a 2 chains structure of sequences from Candida albicans. Full crystallographic information is available from OCA.

Reference

  • Whitlow M, Howard AJ, Stewart D, Hardman KD, Chan JH, Baccanari DP, Tansik RL, Hong JS, Kuyper LF. X-Ray crystal structures of Candida albicans dihydrofolate reductase: high resolution ternary complexes in which the dihydronicotinamide moiety of NADPH is displaced by an inhibitor. J Med Chem. 2001 Aug 30;44(18):2928-32. PMID:11520201

Page seeded by OCA on Tue Feb 17 02:42:54 2009

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