2v1y

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Image:2v1y.png

Template:STRUCTURE 2v1y

STRUCTURE OF A PHOSPHOINOSITIDE 3-KINASE ALPHA ADAPTOR-BINDING DOMAIN (ABD) IN A COMPLEX WITH THE ISH2 DOMAIN FROM P85 ALPHA

Template:ABSTRACT PUBMED 17626883

About this Structure

2V1Y is a 2 chains structure of sequences from Bos taurus and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Miled N, Yan Y, Hon WC, Perisic O, Zvelebil M, Inbar Y, Schneidman-Duhovny D, Wolfson HJ, Backer JM, Williams RL. Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit. Science. 2007 Jul 13;317(5835):239-42. PMID:17626883 doi:317/5835/239

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